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| -Genomic Data for Gli3 |
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- Protein
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- UniPROBE Accession Number
- UP00540
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- Species
- Mus musculus
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- Domain
- zf-H2C2_2
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- Swiss-Prot
- Q61602
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- Name and Synonyms
- Name: GLI-Kruppel family member GLI3.
Synonyms:Transcriptional activator GLI3; add, AI854843, AU023367, Bph, brachyphalangy, GLI3-190, GLI3FL, Pdn, Xt, Zinc finger protein GLI3
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- IHOP
- 121301
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- NCBI RefSeq
- NP_032156
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- Description
- Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repres
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- JASPAR
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None Available
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